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The effect of concurrent radiation and calcium in two cancer cell lines

By May 1, 2018Cancer

The effect of concurrent radiation and calcium in two cancer cell lines

Jessica Billberg

Calcium is an important ubiquitous second messenger regarding the maintenance of cellular homeostasis, and is therefore tightly regulated. Calcium induces cell death when internalised into cancer cells after permeabilization of the cell membrane by electroporation. It is established that radiation causes damage to the lipids and proteins of the cell membrane; and ionizing radiation also causes permeabilization of the cell membrane by peroxidation of the phosphor-lipid layer.

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