SAC and Cancer Therapy
Attacking Cancer In and Out
Cancer is a genetic disease—that is, it is caused by changes to genes that control the way our cells function, especially how they grow and divide and thus multiply without stopping and spread into surrounding tissues. Cancer can start almost anywhere in the human body.
Normally, human cells grow and divide to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place. When cancer develops, however, this orderly process breaks down, and damaged cells survive when they should die and new cells form when they are not needed. These extra cells can divide without stopping and may form growths called tumors. Cancers of the blood, such as leukemia, generally do not form solid tumors.
Cancerous tumors are malignant and invade nearby tissues. Also, some cancer cells can break off and travel to distant places in the body through the blood or the lymph system and form new tumors far from the original tumor.
How Does Cancer Grow and Spread?
How Cancer Cells Grow Uncontrollably
Cancer cells grow out of control and become invasive because they are able to ignore signals that normally tell cells to stop dividing or begin a process known as programmed cell death, or apoptosis, which the body uses to get rid of unneeded cells.
Also, cancer cells are also often able to evade and hide from the immune system that protects the body from infections and other conditions. Tumors can also use the immune system to stay alive and grow. Moreover, cancer cells may be able to influence the normal cells, molecules, and blood vessels that surround and feed a tumor—an area known as the microenvironment.
How Cancer Arises and Spreads
Each person’s cancer has a unique combination of genetic changes. As the cancer continues to grow, additional changes will occur even within the same tumor.
The genetic changes that contribute to cancer tend to affect three main types of genes – proto-oncogenes, tumor suppressor genes, and DNA repair genes. All these genes are involved in normal cell growth, maintenance, and division.
Before cancer cells form in tissues of the body, the cells go through abnormal changes called hyperplasia and dysplasia. In hyperplasia, there is an increase in the number of cells in an organ or tissue that appear normal under a microscope. In dysplasia, the cells look abnormal under a microscope but are not cancer. Hyperplasia and dysplasia may or may not become cancer.
A cancer that has spread from the place where it first started to another place in the body is called metastatic cancer .
In metastasis, cancer cells break away from where they first formed (primary cancer), travel through the blood or lymph system, and form new tumors (metastatic tumors) in other parts of the body.
The metastatic tumor is the same type of cancer as the primary tumor. Metastatic tumors can cause severe damage to how the body functions, and most people who die of cancer die of metastatic disease.
Types of Cancer
There are more than 100 types of cancer. Types of cancer are usually named for the organs or tissues where the cancers form. Cancers also may be described by the type of cell that formed them, such as an epithelial cell or a squamous cell. Here are some categories of cancers that begin in specific types of cells:
Melanoma is cancer that begins in cells that become melanocytes, which are specialized cells that make melanin (the pigment that gives skin its color). Most melanomas form on the skin, but melanomas can also form in other pigmented tissues, such as the eye.
Sarcomas are cancers that form in bone and soft tissues, including muscle, fat, blood vessels, lymph vessels, and fibrous tissue (such as tendons and ligaments). Osteosarcoma is the most common cancer of bone.
Lymphoma is cancer that begins in lymphocytes (T cells or B cells). These are disease-fighting white blood cells that are part of the immune system. In lymphoma, abnormal lymphocytes build up in lymph nodes and lymph vessels, as well as in other organs of the body.
Carcinomas are the most common type of cancer. They are formed by epithelial cells, which are the cells that cover the inside and outside surfaces of the body. There are many types of epithelial cells, which often have a column-like shape when viewed under a microscope.
Multiple myeloma is cancer that begins in plasma cells, another type of immune cell. The abnormal plasma cells, called myeloma cells, build up in the bone marrow and form tumors in bones all through the body.
Cancers that begin in the blood-forming tissue of the bone marrow are called leukemia. These cancers do not form solid tumors. Instead, large numbers of abnormal white blood cells build up in the blood and bone marrow, crowding out normal blood cells. The low level of normal blood cells can make it harder for the body to get oxygen to its tissues, control bleeding, or fight infections.
Types of Treatment for Cancer
There are many types of conventional cancer treatment. The types of treatment that you receive will depend on the type of cancer you have and how advanced it is. The main types of cancer treatment include:
- Radiation Therapy
- Targeted Therapy
- Hormone Therapy
- Stem Cell Transplant
- Precision Medicine
At high doses, radiation kills cancer cells or slows their growth. Radiation therapy is used to either treat cancer or ease cancer symptoms.
Radiation therapy does not kill cancer cells right away. It takes days or weeks of treatment before cancer cells start to die. Then, cancer cells keep dying for weeks or months after radiation therapy ends.
There are two main types of radiation therapy, External Beam Radiation Therapy and Internal Radiation Therapy.
Internal Radiation Therapy
Internal radiation therapy is a treatment in which a source of radiation is put inside your body. The radiation source can be solid or liquid in the form of seeds, ribbons, or capsules placed in your body in or near the cancer. You receive liquid radiation through an IV line. Liquid radiation travels throughout your body, seeking out and killing cancer cells.
External Beam Radiation Therapy
External beam radiation therapy comes from a machine that aims radiation at your cancer and treats a specific part of your body.
Radiation not only kills or slows the growth of cancer cells, it can also affect nearby healthy cells. Damage to healthy cells can cause side effects. The most common side effect of radiation therapy is fatigue, which is feeling exhausted and worn out. Fatigue can happen all at once or little by little. Healthy cells that are damaged during radiation treatment almost always recover after it is over. But sometimes people may have side effects that are severe or do not improve. Other side effects may show up months or years after radiation therapy is over. Doctors try to protect healthy cells during treatment by using as low a dose of radiation as possible, by spreading out treatment over time, and by aiming radiation at a precise part of your body.
Chemotherapy is used to treat many types of cancer. For some people, chemotherapy may be the only treatment you receive. But most often, you will have chemotherapy and other cancer treatments. The types of treatment that you need depends on the type of cancer you have, if it has spread and where, and if you have other health problems.
When used with other treatments, chemotherapy can:
Make a tumor smaller before surgery or radiation therapy, and destroy cancer cells that may remain after treatment with surgery or radiation therapy. Chemotherapy can also help other treatments work better.
Chemotherapy not only kills fast-growing cancer cells, but also kills or slows the growth of healthy cells that grow and divide quickly. Examples are cells that line your mouth and intestines and those that cause your hair to grow. Damage to healthy cells may cause side effects, such as mouth sores, nausea, and hair loss. Side effects often get better or go away after you have finished chemotherapy. The most common side effect is fatigue, which is feeling exhausted and worn out.
One reason that cancer cells thrive is because they are able to hide from your immune system. Certain immunotherapies can mark cancer cells so it is easier for the immune system to find and destroy them. Other immunotherapies boost your immune system to work better against cancer.
Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. The immune system is made up of white blood cells and organs and tissues of the lymph system. Many different types of immunotherapy are used to treat cancer. They include:
These are drugs that are designed to bind to specific targets in the body and cause an immune response that destroys cancer cells. Other types of monoclonal antibodies can “mark” cancer cells so it is easier for the immune system to find and destroy them. These types of monoclonal antibodies may also be referred to as targeted therapy.
Adoptive Cell Transfer
This is a treatment that attempts to boost the natural ability of your T-cells to fight cancer. T-cells are a type of white blood cell and part of the immune system. Researchers isolate T-cells that are most active against your cancer from the tumor and then grow large batches of these T-cells in the lab and then inject them via a needle in your vein.
These are proteins that are made by your body’s cells. They play important roles in the body’s normal immune responses and also in the immune system’s ability to respond to cancer.
These work against cancer by boosting your immune system’s response to cancer cells.
This is an immunotherapy that is used to treat bladder cancer. When weakened form of the bacteria that causes tuberculosis is inserted directly into the bladder with a catheter, BCG causes an immune response against cancer cells.
Immunotherapy can cause side effects. The side effects you may have depend on the type of immunotherapy you receive and how your body reacts to it. The most common side effects are skin reactions at the needle site. These side effects include pain, swelling, soreness, redness, rash, fever, chills, nausea, fatigue, etc.
Ionized Calcium Therapy for Cancer
Calcium Ions Turns Apoptosis Back On
Innovative ionized calcium therapy destroys cancer cells by re-activating muted gene responsible for apoptosis or cell self-destruction. In normal cells, P53 gene triggers cell death when a cell is damaged or aging, allowing new healthy cells to replace it.
However, many cancer cells mass produce NF-kB protein which interferes with the function of P53 gene and turns off apoptosis, causing damaged cells to continue dividing and multiplying. NF-kB is produced in cytoplasm, and then translocated into the nucleus and binds to P53 gene, inhibiting its original functions.
Calcium ions, once introduced into cancer cells, inhibits NF-kB’s effect on P53 gene and therefore restores the function of self-destruction. Cancer cells have only 1% of calcium ions of healthy normal cells, linking widespread calcium deficiency in America to rise of occurrence of cancer for further studies.
In the advanced stage of cancer where P53 gene is damaged beyond repair, calcium ions block lactic acid and inhibit the inflow of glucose into the cells, causing cancer to starve to death.
Calcium ions fight cancer in many other way as well. In pancreatic cancer (90%), intestine cancer, lung cancer and thyroid cancer (50%), liver cancer (30%), and leukemia (30%), RAS inhibitor gene mutation in cancer can be found and Ca++ corrects cancer suppressor gene to normal cell.
Also, in brain tumor, intestine cancer, pancreatic cancer, breast cancer, bladder cancer, lung cancer, and more, cyclooxygenase-2 enzyme (COX-2) is responsible for spreading cancer. Calcium ions inhibit this enzyme by making body fluid alkaline. After all, calcium is our body’s natural acid buffer.
Dietary acids affect your body’s buffering capability, which may cause a calcium loss from your bones to counteract the acidity. Acidosis is caused by kidney disease, dehydration, alcohol, high dietary protein and other health problems. Increased cancer risk is also associated with dietary lifestyles that alter systemic acid-base balance over time and lead to a sub-clinical or low-grade state of metabolic acidosis. The relationship between diet and cancer risk prompts questions about the role of acidosis in the initiation and progression of cancer. SAC counteracts acidosis.
Cell Alkaline Theory
In battling cancer, it is important to eliminate the environment that first caused or nurtured cancer cells. Studies have shown that blood oxygen level of patients with cancer is much lower than that of healthy people. Also, a Nobel prize winner (Otto Warburg, 1883-1970) found that depriving a cell 35% of its oxygen for 48 hours made it cancerous.
There is close relationship between lack of both oxygen and calcium in cancer cells because calcium is responsible for delivering oxygen to intercellular space. Therefore, lack of calcium in cancer cells leads to lack of oxygen which leads to highly acidic environment which cancer favors.
Cancer cells are highly acidic, having pH level of about 4.5. Having enough glucose and not enough oxygen to metabolize it, glucose in cancer cells accumulates as lactic acid through anaerobic glycolysis, also known as fermentation, making cancer cells highly acidic.
Lactic acid produced provides cancer with ideal thriving environment in which to grow and to spread. By making intercellular space reach ideal pH by calcium ions, more influx of oxygen with calcium ions will eliminate cancer-thriving environment.
What do I expect from SAC treatment?
SAC rebuilds underlying health while liberating from many symptoms
Diagnosed with disease
Reliable studies link many major degenerative diseases to calcium deficiency. Yet, most people are calcium deficient due to lifestyle and diet.
Calcium deficiency may be the single most underlying condition that makes us susceptible to hypertension, cancer, diabetes, osteoporosis, Alzheimer’s, arthritis, spinal stenosis, bone spurs, insomnia, kidney stones, heart attack, stroke, etc…
SAC TREATMENT – Phase I
Calcium deficiency reversed by the flow of calcium ions.
Rapid recovery from symptoms begins and maintained by influx of calcium ions. Patient feels better and symptoms may disappear, but improved condition is only maintained by influx of calcium ions. Symptoms may relapse if the influx of calcium ions stop.
6 - 12 months
SAC TREATMENT – Phase II & III
SAC intake must continue despite the absense of symptoms until patient’s body fully recovers to maintain his own health.
SAC serves as scaffolding until body rebuilds itself. Patient continues to feel normal but less and less dependent on SAC as his own health slowly catches up.
SAC MAINTENANCE PROGRAM
Even after patient’s health is restored, maintenance dosage of SAC is recommended to combat calcium deficiency that started health issues in the first place.
Good health is maintained by healthy lifestyle and boost from SAC.
Sample Clinical Cases
Moly Holt : Molly started on Maragen when she stopped taking anticancer medication for her last stage multiple myeloma. After taking Maragen for ten months, her blood test results indicated almost normal. Molly had other benefits from taking SAC treatment. Her rib fracture healed up quickly and even low kidney function improved significantly, and recovered from thrombosis. From osteoporosis, her bone density jumped up to normal range for her age, and she is still cancer free to this date. (2017)When asked, if she felt healthier and stronger after taking Maragen, her reply was a positive “Maybe,” and with a big smile she added, “Thank you very much for giving me Maragen.”
Clinical Example: Molly H. (female, 80 years old) was diagnosed with the last stage multiple myeloma. Upon receiving the SAC Therapy (12/2013), her cancer is now in remission. Her blood work results prove to be in normal range. The dip in 11/2013 is due to chemotherapy which she stopped afterward. In 2016, she and her friend visited Pronuvia and presented the plaque of appreciation. SAC treats blood cancers fast and effectively because of its effect on stem cell in our bones.
Diagnosed Multiple Myeloma in 2013 and her hematological values were far from normal after treatment w/chemo and radiation; However, after treating with SAC for 14 months, her hematological values became normal
Ms. Holt’s hematological data such as Platelet, WBC, and Neutrophil have significantly increased; Ms. Holt’s BMD data also has been significantly improved after treating with SAC
Clinical Example: Yongho Kim (male, 80 years old) was diagnosed with the last stage of leukemia (2013). Upon receiving the SAC therapy for 5 months (12 bottles of MaraGen), his cancer is in remission. The chart below shows noticeable changes in the blood test results within one month. He is fully recovered and healthy as of today (Feb. 2017). Click on the chart to see the full result.
Swim Team Lactic Acid Test after SAC
Animal Tumor Clinical Test
SAC may trigger the increase of cancer markers: As tumors are destroyed by SAC (apoptosis and other anti-cancer effects), marker proteins are dumped into blood vessels and may reflect increased level in blood works. For cancer patients whose health is deteriorating, increasing cancer marker comes with deteriorating blood work. However, patients taking SAC will see improving blood works and feel much better, though often find increased cancer marker, not because the cancer is getting worse but because it is destroyed.
SAC may cause the increase of tumor size: Due to rapid death of cancer cells, tumors are internally filled with fluid and may look bloated and larger. This is not to be mistaken as tumor growth. Tumor density test will reveal decreased tumor density despite the increase of the size. Patients are advised to confirm with tumor density test.
Calcium Ions Assault Cancer Both Within and Without
When popular therapies focus on destroying cancer cells from outside, calcium ion therapy destroys cancer cells both within and without by restoring our body’s natural process for eliminating damaged cells and by eliminating the environment cancer favors.
Pronuvia’s new innovative SAC transport system delivers calcium ions directly into our blood vessels and carries it to every parts of our body affected by cancer, even where chemotherapy has difficulty reaching.
Pronuvia’s SAC Calcium has passive transport movement and moves calcium ions to blood through linings of our digestive system. Calcium ions are the only physiologically active calcium that reacts with genes, stem cells, hormones, and enzymes, etc.
Regular calcium supplements have active transport movement that can only be absorbed with the help of vitamin D and peptide. Such calcium ends up as protein-bound calcium and is not physiologically active and thus not much useful.
Helpful Links for Research Linking Cancer and Calcium
- Switching p53 states by calcium: dynamics and interaction of stress systems
- Where cancer meets calcium — p53 crosstalk with EF-hands
- Regulation of calcium signaling in lung cancer
- Calcium, cancer and killing: The role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells
- Calcium, Magnesium, and Colorectal Cancer
- Vitamin D, calcium, and retinol intake, and pancreatic cancer
- Dairy products, calcium, and prostate cancer risk in the Physicians’ Health Study
- The molecular era of the mitochondrial calcium uniporter