To Help Patients with Dental Problems


The rise of calcium ion level in serum stimulates the release of TH and PTH that balances calcium homeostasis and increases the bone turnover rate by boosting osteoblast which builds bones.  This process helps rebuilds alveolar bones of maxillary and mandible, hence increasing the rate of successful implants or periodontal treatments.

Working in conjunction with bone grafts, Dentigen accelerates the rebuilding of extraction sockets, promotes the integration of grafted bones, and assures better osseointegration of implant material. Complementing bone grafts with Dentigen not only speeds up the procedure but also increases the success rate, even making difficult cases possible for dentists.

Human periodontal ligament stem cells (hPLC) in periodontal ligaments differentiate into root cementum or alveolar bones and are known to be optimally active when the ratio of calcium and phosphorous ions are 2:1.  Dentigen helps the stimulation of hPLC by bringing calcium ion close to the ideal level.

As a stand-alone treatment, 6-9 months of Dentigen supplementation is recommended to build all around stronger dental bone structure including more of filling up extraction socket with natural bones.

Disclaimer: Pronuvia products are not FDA approved for therapeutic purposes.  Unlike drugs, supplements are not intended to treat, diagnose, prevent, or cure diseases. Use with the recommendation of participating health care professional.

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What it does

  • Rebuilds Maxilla & Mandible
  • Activates Periodontal Ligament Stem Cell
  • Assists Bone Graft
  • Restore Gum Health
  • Boost mineralization

Why Dentigen

Dentigen significantly promotes the formation of cementum and induces cementoblastic differentiation of mesenchymal periodontal ligament cells in the bone.

Dentigen, therefore, significantly effects the proliferation, osteogenic differentiation, and mineralization of human Periodontal Ligament Stem Cells(hPDLSCs), which initiates mineralized tissue formation and also regulates cell physiology and maintains the initial mineralization sites. Dentigen is osteoinductive, osteoconductive, and osteogenic.

Formulation: 120ml/ 4.06 fl. oz. liquid

Calcium……….6.4 mg
Magnesium…0.56 mg
Zinc…………….0.2 mg
Selenium……..40 mcg


Other ingredients:
Purified water

Serving Size: 1 tsp (5 ml)
Servings per container: 24

  1. Shake well before use.
  2. Mix 5 ml of the liquid to 500 ml of water
  3. Make sure to drink it in empty stomach. Drink it one hour after or half an hour before any food intake.

Did you know that about 147 diseases are related to calcium?

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